l General Information |
Product Name | (R)-Butaprost |
General description | (R)-Butaprost is a selective EP2 prostanoid receptor agonist. |
Synonym | (1R,2R,3R)-3-Hydroxy-2-[(1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)-1-butenyl]-5-oxo-cyclopentaneheptanoic acid methyl ester |
Purity | ≥98.0%(HPLC) | CAS Number | 69648-38-0 |
Formula | C24H40O5 | Molecular Weight | 408.57 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Light yellow oil |
Solubility(25℃) | DMSO | freely soluble |
Ethanol | freely soluble |
l Biological Information |
Biochem/Physiol Actions |
Butaprost comprises hydroxy-cyclopentanone ring and ω-chain.It aids protection in events of glutamate based N-methyl-D-aspartate receptor toxicity.Butaprost inhibits conjunctival fibrosis and lowers the intraocular pressure in post glaucoma filtration surgery.It also promotes wound healing by reducing the subconjunctival scarring Tenon′s fibroblasts. Butaprost plays a protective role in pulmonary fibrosis and aids protection against the aggregated amyloid β (Aβ) peptides in Alzheimer′s disease. (R)-Butaprost is a selective EP2 prostanoid receptor agonist. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
