l General Information |
Product Name | SC-26196 |
General description | SC-26196 is a Delta6 fatty acid desaturase (Delta6D) inhibitor. |
Synonym | a,a-diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile; 2,2-diphenyl-5-(4-[[(1 E)-pyridin-3-yl-methylidene]amino]piperazin-1-yl)pentanenitr |
Purity | ≥98.0%(HPLC) | CAS Number | 218136-59-5 |
Formula | C27H29N5 | Molecular Weight | 423.55 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to tan Solid |
Solubility(25℃) | DMSO | ≥10mg/mL |
l Biological Information |
Biochem/Physiol Actions | SC-26196 is a Delta6 fatty acid desaturase (Delta6D) inhibitor. It specifically inhibited Delta6D activity with an IC50 value of 100 nM. The rate-limiting step in arachidonic acid synthesis is the desaturation of dietary linoleic acid by Delta6D.SC-26196 completely prevented this conversion of linoleic acid to arachidonic acid. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
