Product Name

5,6-Dehydroarachidonic acid

General description

5,6-Dehydroarachidonic acid inhibits 5-lipoxygenase of guinea pig leukocytes with an IC50 of 10 μM.

Synonym

5,6-dehydro AA, cis-8,11,14-Eicosatrien-5-ynoic acid

Purity

≥98.0%(HPLC)

CAS Number

58688-54-3

Formula

C²⁰H³⁰O²

Molecular Weight

302.45

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Ethanol solution

l  Biological Information

Biochem/Physiol   Actions

Inhibits 5-lipoxygenase of guinea pig leukocytes with an IC50 of 10 μM. In extracts of rat basophilic leukemia cells preincubated with 5,6-dehydro AA, the Ki for the conversion of arachidonic acid to 5-HPETE is 15 μM.

l  Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov