l General Information |
Product Name | NCX 4040 |
General description | NCX 4040 is a nitric oxide-donating form of aspirin. |
Synonym | NO-aspirin |
Purity | ≥98.0%(HPLC) | CAS Number | 287118-97-2 |
Formula | C16H13NO7 | Molecular Weight | 331.28 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to beige Solid |
Solubility(25℃) | DMSO | ≥10mg/mL |
l Biological Information |
Biochem/Physiol Actions | NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine , and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
