l General Information |
Product Name | Ibufenac |
General description | Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen. |
Purity | ≥95.0%(HPLC) | CAS Number | 1553-60-2 |
Formula | C12H16O2 | Molecular Weight | 192.25 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to beige Solid |
Solubility(25℃) | DMSO | ≥15mg/mL |
l Biological Information |
Biochem/Physiol Actions | Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen that was withdrawn for hepatotoxicity. It inhibits cyclooxygenases COX-1 and -2 activity with IC50 values of 17.4 and 13.1 μM, respectively and > 40 μM for 5-LOX. It has been used in studies of drug-induced hepatotoxicity. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
