l General Information |
Product Name | Topoisomerase II α human (Single band on SDS-PAGE) |
General deion | Topoisomerase II α (TopoIIα) is a gene product with conserved catalytic activities and it promotes the progression of DNA damage. The α isoform is present in proliferating cells. |
Synonym | p170 |
Molecular Weight | mol wt 170 kDa | MDL number | MFCD03458766 |
Suitability | BioReagent |
l Physical and Chemical Information |
Physical form | Buffered aqueous glycerol solution, containing Trizma buffer (pH 7.7). |
l Biological Information |
Biochem/Physiol Actions | Used to study DNA structure and topology. |
Application | Topoisomerase II α has been used in a study to assess aging processes in the human brain. Topoisomerase II α has also been used in a study to investigate its activity in HIV-1 replication. |
Unit Definition | One unit will decatenate 0.2 μg of kinetoplast DNA in 30 minutes at 37°C. |
l Storage |
Storage temp. | −70°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
