Product Name

Phosphoglucose Isomerase from rabbit muscle

Synonym

D-Glucose-6-phosphate ketol-isomerase, PGI, Phosphosaccharomutase

Assay

Type XI, ≥200 units/mg protein; protein, 70-100% biuret

CAS Number

9001-41-6

MDL number

MFCD00131887

Suitability

BioReagent

l Physical and Chemical Information

Appearance

lyophilized powder

l Biological Information

Biochem/Physiol Actions

Phosphoglucose Isomerase fuctions as an isomerase, neuroleukin, autocrine motility factor, and a differentiation and maturation mediator. It is responsible for the photosynthetic reduction of carbon.

Application

Phosphoglucose Isomerase (PGI) is an enzyme crucial for the interconversion of D-glucose 6-phosphate and D-fructose 6-phosphate. PGI is responsible for the second step of glycolysis and is involved in glucogenesis. It is highly conserved in bacteria and eukaryotes. It is used in sugar assays to convert fructose to glucose. The product is type XI and is from rabbit muscle. It is useful in enzyme systems requiring low sulfate.

Preparation Note

Essentially sulfate-free powder containing citrate buffer salts

Unit Definition

One unit will convert 1.0 μmole of D-fructose 6-phosphate to D-glucose 6-phosphate per min at pH 7.4 at 25 °C.

l Storage

Storage temp.

-20°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov