Glyoxalase I from Saccharomyces cerevisiae
Product #：
S0841
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SKU-Pack Size
Stock
Price($)
Quantity
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S0841-200UN
In-stock
267.8
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S0841-500UN
In-stock
538.2
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S0841-1KU
In-stock
1081.6
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Details
l General Information |
Product Name | Glyoxalase I from Saccharomyces cerevisiae |
General deion | Glyoxalase detoxification system consists of glyoxalase (GLO)-I and GLO-II. GLO-I is a cytosolic, 42 kDa, dimeric Zn2+metalloenzyme. |
Synonym | S-Lactoyl-glutathione methylglyoxal-lyase (isomerizing) |
Assay | Grade IV,≥400 units/mg protein |
CAS Number | 9033-12-9 | MDL number | MFCD00131225 |
Suitability | BioReagent |
l Physical and Chemical Information |
Appearance | Colorless to Light Tan buffered aqueous glycerol solution; Clear to Slightly Hazy |
l Biological Information |
Biochem/Physiol Actions | Glyoxalase I is universally expressed and involved in the protection against cellular damage due to cytotoxic metabolites such as advanced glycation end products (AGEs). It is an integral component of the detoxification system, catalyzing the conversion of reactive, acyclic a-oxoaldehydes into the corresponding a-hydroxyacids in a glutathione-dependent manner. |
Preparation Note | Solution in 50% glycerol, 0.4 M (NH4)2SO4 and 0.002 M KH2PO4 pH 6.5 |
Unit Definition | One unit will form 1.0 μmole of S-lactoylglutathione from methylglyoxal and reduced glutathione per min at pH 6.6 at 25 °C. |
l Storage |
Storage temp. | 2-8°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
