Product Name

Adenosine deaminase chicken, recombinant

Synonym

ADA

Assay

recombinant, expressed in E. coli, ≥0.5 U/mL

Suitability

BioReagent

l Physical and Chemical Information

Appearance

Solution

l Biological Information

Biochem/Physiol Actions

Adenosine deaminase irreversibly deaminates adenosine to inosine. In addition to immune system regulation, ADA may be involved in epithelial cell differentiation, neurotransmission and gestation maintenance.

Application

Adenosine deaminase (ADA) is a key enzyme in purine metabolism and is essential for normal immune function. It is important in the study of immune system diseases such as rheumatoid arthritis.

Unit Definition

One unit will deaminate 1.0 μmole of adenosine to inosine per min at pH 7.5 at 25°C.

l Storage

Storage temp.

-20°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov