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Home > Products > Life sciences > Enzymes and proteins > Acylase I from porcine kidney

Acylase I from porcine kidney

Product #: S0755
Image SKU-Pack Size Stock Price($) Quantity
  • S0755-100MG

    In-stock

    233

    - +

    S0755-500MG

    In-stock

    686.4

    - +

    S0755-1G

    In-stock

    1183

    - +

    S0755-5G

    4654

    - +

Documents

Details

l General Information

Product Name

Acylase I from porcine kidney

Synonym

Aminoacylase, N-Acylamino acid amidohydrolase

Assay

Grade I,≥1500 units/mg protein; Protein, ≥60%

CAS Number

9012-37-7

MDL number

MFCD00081285

Suitability

BioReagent

l Physical and Chemical Information

Appearance

White to Light Brown lyophilized powder

l Biological Information

Biochem/Physiol Actions

Acylase I catalyzes the deacetylation of N-acetyl-L-cysteine and S-alkyl-N-acetyl-L-cysteines. n-Butylmalonic acid is an inhibitor of acylase I. S-alkyl-N-acetyl-L-cysteines with short (C0-C3) and unbranched S-alkyl substituents have been found to be good acylase I substrates .

Application

Acylase I from porcine kidney has been used to study the acylase I-catalyzed deacetylation of various S-alkyl-N-acetyl-L-cysteines and their carbon and oxygen analogues . Acylase I may be useful to catalyze N-acetyl amino acids to enantiomerically pure L-amino acids.

Preparation Note

This enzyme is soluble in potassium phosphate buffer, pH 7.0, (1 mg/ml), yielding a clear solution.

Unit Definition

One unit will hydrolyze 1.0 μmole of N-acetyl-L-methionine per hr at pH 7.0 at 25 °C.

l Storage

Storage temp.

-20°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov

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