Product Name

Lysostaphin from Staphylococcus simulans

Synonym

Glycyl-glycine Endopeptidase

Assay

≥90% (HPLC); ≥3000 unit/mg solid; recombinant, expressed in E. coli

CAS Number

9011-93-2

MDL number

MFCD00131556

Suitability

BioReagent

l Physical and Chemical Information

Appearance

White to Off-White Lyophilized Powder

l Biological Information

Biochem/Physiol Actions

A protein complex with highly specific lytic activity against Staphylococcus species, including Staphylococcus aureus.

The antimicrobial activity of lysostaphin, a metalloendopeptidase expressed by Staphylococcus simulans, is enhanced by binding to the C′ terminus of the membrane-associated Trap protein of Staphylococcus aureus.

Application

Lysostaphin from Staphylococcus simulans has been used in a study to assess molecular cloning, sequencing, and  of lytM, a unique autolytic gene of Staphylococcus aureus. It has also been used in a study to investigate the sequence analysis of a Staphylococcus aureus gene encoding a peptidoglycan hydrolase activity.

l Storage

Storage temp.

-20°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov