Product Name

Lysostaphin from Staphylococcus staphylolyticus

Synonym

Glycyl-glycine Endopeptidase

Assay

Protein 50-70 % by biuret, ≥500 units/mg protein

CAS Number

9011-93-2

MDL number

MFCD00131556

Suitability

BioReagent

l Physical and Chemical Information

Appearance

White to Light Yellowt Lyophilized Powder

l Biological Information

Biochem/Physiol Actions

Lysostaphin is a zinc endopeptidase with a molecular weight of approximately 25 kDa. Because lysostaphin cleaves the polyglycine cross-s in the peptidoglycan layer of the cell wall of Staphylococcus species it has been found useful for cell lysis and also as a potential anti-microbial therapeutic.

pH Optimum for activity: ~7.5

Unit Definition

One unit will reduce the turbidity (A₆₂₀) of a suspension of Staphylococcus aureus cells from 0.250 to 0.125 in 10 min at pH 7.5 at 37°C in a 6.0 ml reaction mixture.

l Storage

Storage temp.

-20°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov