Cathepsin D from bovine spleen
Product #：
S0700
Image
SKU-Pack Size
Stock
Price($)
Quantity
-
-
S0700-5UN
In-stock
548.6
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+
S0700-10UN
In-stock
941.2
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S0700-20UN
In-stock
1677
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S0700-40UN
In-stock
3068
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+
Details
l General Information |
Product Name | Cathepsin D from bovine spleen |
Assay | ≥2.0 units/mg protein | CAS Number | 9025-26-7 |
Molecular Weight | mol wt ~45 kDa | MDL number | MFCD00130749 |
Suitability | BioReagent |
l Physical and Chemical Information |
Physical form | Lyophilized powder containing citrate buffer salts |
l Biological Information |
Biochem/Physiol Actions | Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimer’s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane potential in apoptotic human foreskin fibroblasts. Cathepsin D levels in PC12 cells increase 12 to 24 hours after apoptosis is induced. |
Unit Definition | One unit will produce an increase in A280 of 1.0 per min per mL at pH 3.0 at 37 °C measured as TCA-soluble products using hemoglobin as substrate (1 cm light path). |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
