Clostripain from Clostridium histolyticum
Product #:
S0691
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S0691-250UN
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1599
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Details
l General Information |
Product Name | Clostripain from Clostridium histolyticum |
Synonym | Clostridiopeptidase B, Proteinase from Clostridium histolyticum |
Assay | ≥20 units/mg solid |
CAS Number | 9028-00-6 | MDL number | MFCD00130814 |
Suitability | BioReagent |
l Physical and Chemical Information |
Appearance | salt, essentially free; Lyophilized Powder |
l Biological Information |
Biochem/Physiol Actions | Clostripain from Clostridium histolyticum is composed of two polypeptide chains, with molecular masses of 41.7 kDa and 15.4 kDa. Clostripain has a highly restricted substrate specificity for Arg-Xaa peptide bonds. Therefore, clostripain has been explored as a potential enzyme for protein sequencing purposes. It has also been studied as a catalyst for condensation of pharmaceutically important peptides containing Arg-Pro bonds. |
Unit Definition | One unit will hydrolyze 1.0 μmole of BAEE per min at pH 7.6 at 25 °C in the presence of 2.5 mM DTT. |
l Storage |
Storage temp. | 2-8°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |