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Home > Products > Life sciences > Enzymes and proteins > Clostripain from Clostridium histolyticum

Clostripain from Clostridium histolyticum

Product #: S0691
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Details

l General Information

Product Name

Clostripain from Clostridium histolyticum

Synonym

Clostridiopeptidase B, Proteinase from Clostridium histolyticum

Assay

≥20 units/mg solid

CAS Number

9028-00-6

MDL number

MFCD00130814

Suitability

BioReagent

l Physical and Chemical Information

Appearance

salt, essentially free; Lyophilized Powder

l Biological Information

Biochem/Physiol Actions

Clostripain from Clostridium histolyticum is composed of two polypeptide chains, with molecular masses of 41.7 kDa and 15.4 kDa. Clostripain has a highly restricted substrate specificity for Arg-Xaa peptide bonds. Therefore, clostripain has been explored as a potential enzyme for protein sequencing purposes. It has also been studied as a catalyst for condensation of pharmaceutically important peptides containing Arg-Pro bonds.

Unit Definition

One unit will hydrolyze 1.0 μmole of BAEE per min at pH 7.6 at 25 °C in the presence of 2.5 mM DTT.

l Storage

Storage temp.

2-8°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov

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