Product Name

Thrombin human

General deion

Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects.

Synonym

Factor Iia

Assay

BioUltra, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE); ≥2,000 units/mg protein

MDL number

MFCD00082072

Suitability

BioReagent

l Physical and Chemical Information

Appearance

Colorless aqueous solution

Physical form

supplied as a solution in 20 mM MES, pH 6.0, 500 mM choline chloride

l Biological Information

Application

Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to assess in vitro hemostatic properties of French lyophilized plasma.

Preparation Note

supplied as a solution in 20 mM MES, pH 6.0, 500 mM choline chloride

l Storage

Storage temp.

−70°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov