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Home > Products > Life sciences > Enzymes and proteins > Thrombin from human plasma

Thrombin from human plasma

Product #: S0641
Image SKU-Pack Size Stock Price($) Quantity
  • S0641-100UN

    In-stock

    280.8

    - +

    S0641-250UN

    In-stock

    556.4

    - +

    S0641-1KU

    In-stock

    1497.6

    - +

    S0641-5KU

    In-stock

    6006

    - +

Documents

Details

l General Information

Product Name

Thrombin from human plasma

General deion

Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects.

Synonym

Factor Iia

Assay

≥2,000 NIH units/mg protein (E1%/280, 18.3)

CAS Number

9002-04-4

MDL number

MFCD00082072

Suitability

BioReagent

l Physical and Chemical Information

Appearance

White to Off-White lyophilized powder

Solubility(25°C)

250 NIH units/mL, H2O; Colorless; Clear

l Biological Information

Biochem/Physiol Actions

Serine protease that selectively cleaves Arg-Gly bonds in fibrinogen to form fibrin and fibrinopeptides A and B.

Application

Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to investigate the protein C pathway in intestinal barrier function.

Preparation Note

Lyophilized from saline sodium citrate buffer, pH 6.5. The product is soluble in water (10 mg/mL).

Unit Definition

Activity is expressed in NIH units obtained by direct comparison to a NIH Thrombin Reference Standard

l Storage

Storage temp.

-20°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov

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