l General Information |
Product Name | Thrombin from rat plasma |
General deion | Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects. |
Assay | ≥1,000 units/mg protein (biuret) |
CAS Number | 9002-04-4 | MDL number | MFCD02179676 |
Suitability | BioReagent |
l Physical and Chemical Information |
Appearance | lyophilized powder |
Physical form | Lyophilized from saline sodium citrate buffer, pH 6.5 |
l Biological Information |
Biochem/Physiol Actions | Serine protease that selectively cleaves Arg-Gly bonds in fibrinogen to form fibrin and fibrinopeptides A and B. |
Application | Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to investigate activation of equine platelet-rich plasma. |
Preparation Note | Lyophilized from saline sodium citrate buffer, pH 6.5. |
Unit Definition | Activity is expressed in NIH units obtained by direct comparison to a NIH Thrombin Reference Standard, Lot K. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
