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Home > Products > Life sciences > Enzymes and proteins > Angiotensin Converting Enzyme from porcine kidney

Angiotensin Converting Enzyme from porcine kidney

Product #: S0588
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l General Information

Product Name

Angiotensin Converting Enzyme from porcine kidney

General deion

ACE is a monomer with molecular weight of ~170 kDa

pH range for activity: 7-8.5

Temperature optimum: 37 °C

Zinc is required for activity

Inhibitors: captopril, enalaprilat, lisinopril etc. (1-10 μM)

Synonym

ACE, Peptidyl-dipeptidase A

Assay

≥10 units/mg protein (Bradford)

CAS Number

9015-82-1

MDL number

MFCD00130325

Suitability

BioReagent

l Physical and Chemical Information

Appearance

lyophilized powder

Physical form

Lyophilized powder containing Tris buffer salts.

l Biological Information

Biochem/Physiol Actions

Removes C-terminal dipeptides from susceptible substrates, e.g., angiotensin I and bradykinin.

Unit Definition

One unit will produce 1.0 ·μmole of hippuric acid from Hippuryl-His-Leu per min in 50 mM HEPES and 300 mM NaCl at pH 8.3 at 37 °C.

l Storage

Storage temp.

-20 °C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov

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