Product Name

NADase from porcine brain

General deion

NADase is a glycohydrolase that catalyzes ADP-ribose transfer.

Synonym

DPN Nucleosidase, NAD₊ glycohydrolase

Assay

≥0.007 unit/mg solid

CAS Number

9032-65-9

MDL number

MFCD00131705

Suitability

BioReagent

l Physical and Chemical Information

Appearance

Off White to Light Beige to Light Brown Powder

Physical form

Acetone-dried powder

Solubility(25°C)

insoluble

l Biological Information

Biochem/Physiol Actions

Nicotinamide has been shown to inhibit NADase activity.

Application

NADase from porcine brain has been used in a study to investigate histidine and related compounds resulting from catalyzed ADP-riboslyation. It has also been used in a study to investigate the preparation of arylazide-substituted pyridine adenine dinucleotides for photoaffinity labeling.

Unit Definition

One unit will hydrolyze 1.0 μmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37 °C.

l Storage

Storage temp.

-20°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov