β-Glucuronidase from limpets (Patella vulgata)
Product #：
S0528
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SKU-Pack Size
Stock
Price($)
Quantity
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S0528-100KU
In-stock
170
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+
S0528-250KU
In-stock
332.8
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S0528-500KU
In-stock
559
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S0528-1MU
In-stock
904.8
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S0528-2MU
In-stock
1528.8
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+
Details
l General Information |
Product Name | β-Glucuronidase from limpets (Patella vulgata) |
Synonym | β-D-Glucuronide glucuronosohydrolase |
Assay | Type L-II, 1,000,000-3,000,000 units/g solid |
CAS Number | 9001-45-0 | MDL number | MFCD00130629 |
Suitability | BioReagent |
l Physical and Chemical Information |
Appearance | lyophilized powder |
l Biological Information |
Biochem/Physiol Actions | β-glucuronidase (β-GIc) is an exoglycosidase that catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making bilirubin suitable for reabsorption. Morphine 3-β-D glucuronide was converted to morphine using ß-glucuronidase obtained from Patella vulgate. |
Application | New Technical Article Comparing Performance of Different Enzymes The enzyme from patella vulgata is reported to be more effective in hydrolyzing opioid-glucuronides than the Helix pomatia, bovine liver and E. coli enzymes β-Glucuronidase Type L-II has been shown to be a superior enzyme for the hydrolysis of drug-glucuronides from urine |
Unit Definition | One modified Fishman unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37 °C at pH 3.8 (30 min assay). |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
