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PDE4A4B active human

Product #: S0412
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Details

l General Information

Product Name

PDE4A4B active human

General deion

Human PDE4A4B, also known as PDE4A isoform 1 (GenBank Accession No. NM_001111307) amino acids 2-end with N-terminal GST-tag, MW= 124 kDa, expressed in a Baculovirus infected Sf9 cell system.

Synonym

DPDE2, PDE46, phosphodiesterase 4A, cAMP-specific

Assay

recombinant, expressed in baculovirus infected Sf9 cells, ≥40% (SDS-PAGE)

Molecular Weight

mol wt 124 kDa

Suitability

BioReagent

l Physical and Chemical Information

Appearance

aqueous solution

l Biological Information

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Unit Definition

One unit is defined as the amount of enzyme that will convert 1 pmole of 3’, 5’-cAMP to 5’-AMP per min at 37°C.

l Storage

Storage temp.

−70°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov

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