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PDE4A10 active human

Product #: S0411
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l General Information

Product Name

PDE4A10 active human

General deion

Human PDE4A10, also known as PDE4A protein isoform 6, tran variant 3 (GenBank Accession No. NM_001111309) amino acids 2-825 (end) with N-terminal GST-tag, MW= 117 kDa, expressed in a Baculovirus infected Sf9 cell  system.

Synonym

DPDE2, PDE46, phosphodiesterase 4A, cAMP-specific

Assay

recombinant, expressed in baculovirus infected Sf9 cells, ≥75% (SDS-PAGE)

Molecular Weight

mol wt 117 kDa

Suitability

BioReagent

l Physical and Chemical Information

Appearance

aqueous solution

l Biological Information

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Unit Definition

One unit is defined as the amount of enzyme that will convert 1 pmole of 3’, 5’-cAMP to 5’-AMP per min at 37°C.

l Storage

Storage temp.

−70°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov

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