l General Information |
Product Name | Phosphodiesterase 3B |
Synonym | 3′,5′-cyclic-nucleotide phosphodiesterase, PDE 3B |
Assay | recombinant, expressed in Sf9 cells; ≥3,000 units/μg protein |
MDL number | MFCD00131864 |
Suitability | BioReagent |
l Physical and Chemical Information |
Physical form | Supplied as a solution in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT |
l Biological Information |
Application | Phosphodiesterase 3B has been used in a study to evaluate the evidence for biological effects of metformin in operable breast cancer. Phosphodiesterase 3B has also been used in a study to investigate the role of intracellular and intercellular communication in perfusion distribution of erythrocyte-derived ATP. |
Unit Definition | One unit will convert 1.0 picomole of 3′,5′-cAMP to 5′-AMP per minute at pH 7.4 at 37 °C. |
l Storage |
Storage temp. | −70°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
