Ribonuclease A from bovine pancreas
Product #：
S0342
Image
SKU-Pack Size
Stock
Price($)
Quantity
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S0342-100MG
In-stock
207.4
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+
S0342-500MG
In-stock
642.2
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S0342-1G
In-stock
1227.2
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S0342-5G
In-stock
4238
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+
Details
l General Information |
Product Name | Ribonuclease A from bovine pancreas |
Synonym | Pancreatic Ribonuclease, RNase A, Ribonucleate 3′-pyrimidinooligonucleotidohydrolase |
Assay | ≥60% RNase A basis (SDS-PAGE), ≥50 Kunitz units/mg protein; Type I-A | CAS Number | 9001-99-4 |
Molecular Weight | mol wt ~13,700 | MDL number | MFCD00132181 |
Suitability | BioReagent |
l Physical and Chemical Information |
Appearance | White to Off-White powder |
l Biological Information |
Biochem/Physiol Actions | Ribonuclease A is an endoribonuclease that cleaves single stranded RNA after pyrimidine nucleotides. It attacks at the 3’ phosphate end. Ribonucleases do not hydrolyze DNA, because the DNA lacks 2′-OH groups essential for the formation of cyclic intermediates. RNase can also hydrolyze RNA from protein samples. RNase A can be inhibited by alkylation of His12and His119 and activated by potassium and sodium salts. |
Application | Ribonuclease A is used to remove RNA from DNA plasmid preparations and protein samples. It is also used in RNA sequence analysis and protection assays. RNase has been used as a tool for computer-aided drug design . |
Preparation Note | Salt fractionated and chromatographically purified. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
