l General Information |
Product Name | NMNAT1 human |
General deion | Nuclear NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed. |
Synonym | EC 2.7.7.1, IL-1F9, NMN adenylyltransferase 1, Nicotinamide mononucleotide adenylyltransferase 1 |
Assay | >95% (SDS-PAGE); recombinant, expressed in E. coli, His tagged |
Molecular Weight | monomer mol wt ~33.3 kDa |
Suitability | BioReagent |
l Physical and Chemical Information |
Appearance | clear liquid |
Physical form | Solution in 50 mM sodium phosphate, pH 8.0, containing 300 mM sodium chloride, 2 mM DTT and 10% glycerol. |
l Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
