Product Name

Uricase from Arthrobacter globiformis

Synonym

Urate oxidase, Urate:O² oxidoreductase

Assay

15-30 units/mg protein (biuret)

CAS Number

9002-12-4

MDL number

MFCD00082126

Suitability

BioReagent

l Physical and Chemical Information

Appearance

lyophilized powder

l Biological Information

Biochem/Physiol Actions

Molecular weight: 4 × ~32 KDa (tetramer) 

Isoelectric point: is 4.64

KM value (uric acid as substrate): ~ 0.01 mM

The optimum pH for activity: 8.5-9.5

The optimum pH for stability: 6.0-9.5

Zn and Cu were shown to inhibit the activity of uricase.

Unit Definition

One unit will convert 1.0 μmole of uric acid to allantoin per min at pH 9.0 at 25 °C.

l Storage

Storage temp.

-20°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov