Product Name

Monoamine Oxidase A human

General deion

Monoamine Oxidase A contains binding sites for 8α-S-cysteinyl-FAD.

Synonym

MAO-A, MAOA

Assay

~2.5 mg per vial; Protein: ≥3.0mg/ml; Activity: ≥10units/mg protein; recombinant, expressed in baculovirus infected BTI insect cells

MDL number

MFCD04040932

Suitability

BioReagent

l Biological Information

Biochem/Physiol Actions

MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.

Application

Monoamine Oxidase A has been used in a study to assess abnormal behavior in a large kindred of males where a deficiency of enzymatic activity of monamine oxidase A was found.  It has also been used in a study to investigate an association between smoking and the inhibition of MAOA.

Preparation Note

It is recommended that the product be thawed rapidly in a 37 °C water bath and kept on ice until use.

l Packaging & Storage

Storage temp.

The product ships on dry ice and it is recommended to store the product at -70 °C. Avoid repeated freeze-thaw cycles.

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov