Product Name

Formate Dehydrogenase from Candida boidinii

General deion

FDH is an abundant enzyme from yeast Candida boidinii (CbFDH) that plays an important role in the energy supply of methylotrophic microorganisms and in the stress response of plants.

Synonym

FDH, Formate:NAD₊ oxidoreductase

Assay

5.0-15.0 units/mg protein

CAS Number

9028-85-7

MDL number

MFCD00081614

Suitability

BioReagent

l Physical and Chemical Information

Appearance

lyophilized powder

l Biological Information

Biochem/Physiol Actions

Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD₊ to NADH.

Application

Formate Dehydrogenase (FDH) is used for diagnostics in large scale industrial processes. Its used in the production of an unnatural amino acid, tert-L-leucine, a component of some HIV protease and matrix metalloprotease inhibitors.

Unit Definition

One unit will oxidize 1.0 μmole of formate to CO² per min in the presence of β-NAD at pH 7.6 at 37 °C.

l Packaging & Storage

Storage temp.

2-8°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov