Product Name

Glyceraldehyde-3-phosphate Dehydrogenase from baker's yeast (S. cerevisiae)

Synonym

D-Glyceraldehyde 3-phosphate:NAD₊ oxidoreductase (phosphorylating), GAPDH

Assay

70-140 units/mg protein

CAS Number

9001-50-7

MDL number

MFCD00131203

Suitability

BioReagent

l Physical and Chemical Information

Appearance

lyophilized powder

Physical form

Lyophilized, sulfate-free powder stabilized with trehalose, citrate, and DTT. Useful for systems requiring low sulfate.

l Biological Information

Biochem/Physiol Actions

Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, tranion activation and the shuttling of ER to Golgi vesicles.

Unit Definition

One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25 °C.

l Storage

Storage temp.

-20°C

l Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l References

1. http://www.drugbank.ca

2. https://ncit.nci.nih.gov

3. https://www.ncbi.nlm.nih.gov