Superoxide Dismutase from bovine erythrocytes
Product #:
S0118
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SKU-Pack Size
Stock
Price($)
Quantity
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S0118-15KU
In-stock
188.8
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+
S0118-30KU
In-stock
254.2
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S0118-75KU
In-stock
423.8
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S0118-300KU
In-stock
1274
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Details
l General Information |
Product Name | Superoxide Dismutase from bovine erythrocytes |
General deion | Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals and micro-organisms. They provide protection against damaging reactions with the superoxide radical anion (O2-) by catalyzing its disproportionation into oxygen and hydrogen peroxide. |
Synonym | SOD, Superoxide: superoxide oxidoreductase |
Assay | ≥3,000 units/mg protein |
CAS Number | 9054-89-1 | MDL number | MFCD00132404 |
Suitability | BioReagent |
l Physical and Chemical Information |
Appearance | lyophilized powder |
Physical form | Lyophilized powder, essentially salt-free |
l Biological Information |
Biochem/Physiol Actions | Catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. Plays a critical role in the defense of cells against the toxic effects of oxygen radicals. Competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice. |
Application | Superoxide dismutase from bovine erythrocytes has been used in a study to assess a kinetic model of radiation-induced inactivation of superoxide dismutase in nitrous oxide-saturated solutions. Superoxide dismutase from bovine erythrocytes has also been used in a study to investigate the possible participation of superoxide anion in the intestinal tryptophan 2,3-dioxygenase reaction. |
Unit Definition | One unit will inhibit reduction of cytochrome c by 50% in a coupled system with xanthine oxidase at pH 7.8 at 25 °C in a 3.0 ml reaction volume. Xanthine oxidase concentration should produce an initial ΔA550 of 0.025 ± 0.005 per min. |
l Packaging & Storage |
Storage temp. | -20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |