L-Lactic Dehydrogenase from rabbit muscle
Product #：
S0023
Image
SKU-Pack Size
Stock
Price($)
Quantity
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S0023-5KU
In-stock
113.8
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+
S0023-10KU
In-stock
196.8
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S0023-25KU
In-stock
377
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S0023-50KU
In-stock
699.4
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S0023-100KU
In-stock
1232.4
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Details
l General Information |
Product Name | L-Lactic Dehydrogenase from rabbit muscle |
General deion | L-lactic dehydrogenase catalyzes the conversion of L-lactate into L-pyruvate while reducing NAD+ to NADH and H+. |
Synonym | (S)-Lactate: NAD+ oxidoreductase, L-LDH, LAD, LD, Lactate |
Assay | 800-1,200 units/mg protein | CAS Number | 9001-60-9 |
MDL number | MFCD00131466 |
Suitability | BioReagent |
l Physical and Chemical Information |
Appearance | ammonium sulfate suspension |
l Biological Information |
Biochem/Physiol Actions | Also catalyzes the oxidation of other L-2-hydroxymonocarboxylic acids. Lactic Dehydrogenase (LDH) has a total molecular weight of 140 kDa and is composed of 4 subunits which are designated M subunit (muscle) and H subunit (heart).These subunits may be mixed in any of 5 combinations (M4, M3H1, M2H2, MH3, and H4).Skeletal muscle contains LDH that is predominately M4 with some small amounts of M3H and traces of H2H2. The H and M subunits are quite similar in molecular weight, but differ substantially in amino acid composition. Rabbit muscle LDH dissociates into dimeric species (MW = ~70 kDa) in acetate-chloride at pH 5.0, the dissociation is reversible. Biochemistry, 13, 3527-3531 (1974). Oxidizes glyoxylate and lactate. Isoelectric point: 8.4-8.6 Optimal pH : 7.5 . |
Unit Definition | One unit will reduce 1.0 μmole of pyruvate to L-lactate per min at pH 7.5 at 37 °C. |
l Packaging & Storage |
Storage temp. | 2-8°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
