Product Name

Alcohol Dehydrogenase, recombinant from E. coli

General deion

Alcohol dehydrogenase catalyzes the oxidative conversion of alcohol into aldehyde.

Synonym

Alcohol:NADP₊ oxidoreductase

Assay

≥500 U/mL

CAS Number

9028-12-0

MDL number

MFCD00130451

Suitability

BioReagent

l  Biological Information

Biochem/Physiol Actions

Alcohol dehydrogenase catalyzes the oxidative conversion of alcohol into aldehyde. It has a homodimeric structure with a co-enzyme binding domain at the C-terminal and an N-terminal catalytic domain. The active site is located at the interdomain cleft. Binding of NAD₊  in the active site causes conformational changes which create the binding site for the alcohol substrate.

Unit Definition

1 U corresponds to the amount of enzyme which  reduces 1 μmol acetone per minute at pH 7.0 and 30°C (NADPH as cofactor)

l  Packaging & Storage

Storage temp.

-20℃

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov