Phone: +86-20-31155029 | Tech Support:tech@tomums.cn | Email:sales@tomums.cn
Home > Products > Bioactive Molecule >NeuronalSignaling > AZD3839(free base)

AZD3839(free base)

Product#:TL0101
Image SKU-Pack Size Stock Price Quantity
  • TL0101-5MG

    5

    $ : 198.00

    -+

    TL0101-25MG

    5

    $ : 636.00

    -+

    TL0101-100MG

    2

    $ : 1080.00

    -+

DETAILS

l  General Information

Product Name

AZD3839(free base)

General description

AZD3839 is a potent and selective BACE1 inhibitor.

Synonym

(3S)-3-[2-(difluoromethyl)pyridin-4-yl]-7-fluoro-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine; CHEMBL2177913;  AZD-3839

Purity

≥98% (HPLC)

CAS Number

1227163-84-9

Formula

C24H16F3N5

Molecular Weight

431.422

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to pale yellow solid

Solubility(25)

DMSO

≥50mg/mL

Ethanol

≥50mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol Actions

AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. It has been used in trials studying the basic science of Safety, Tolerability, Alzheimer's Disease, and Blood Concentration.

l  Packaging & Storage

Packaging

5mg; 25mg; 100mg

Storage temp.

0-5

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov