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Home > Products > Bioactive Molecule >Microbiology > Fumagillin

Fumagillin

Product#:TL0168
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DETAILS

l  General Information

Product Name

Fumagillin

General description

Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2).

Synonym

(2E,4E,6E,8E)-10-[[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid; Fumagilline; Fumagillinum; Fumagilina; Fugillin; Fumidil

Purity

≥96%(HPLC)

CAS Number

23110-15-8

Formula

C26H34O7

Molecular Weight

458.551

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Pale yellow or Brownish yellow solid

Solubility(25)

DMSO

≥50mg/mL

Ethanol

≥25mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol Actions

Methionine aminopeptidase-2 (MetAP-2) inhibitor; inhibits endothelial cell proliferation and angiogenesis.

Application

1. Angiogenesis Inhibitors

2. Anti-Bacterial Agents

3. Antiprotozoal Agents

l  Packaging & Storage

Packaging

5mg; 25mg

Storage temp.

-20

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov